Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway
The number of stem/progenitor cells Custom Shape Necklace available can profoundly impact tissue homeostasis and the response to injury or disease.Here, we propose that an atypical PKC, Prkci, is a key player in regulating the switch from an expansion to a differentiation/maintenance phase via regulation of Notch, thus linking the polarity pathway